Emcelle

What Is Vitamin E?

Vitamin E is a fat-soluble, vitamin involved in the metabolism of all cells. Vitamin E acts as an antioxidant to protect the molecular structure of cells against the destabilizing oxidation effects of free radicals, often caused simply as by-products of energy metabolism. Free radicals can damage cells, break down body tissue and contribute to disease development.

In calves, Vitamin E deficiency can critically affect tongue musculature resulting in a reduction of suckling. Other symptoms of calf deficiency are muscular dystrophy affecting skeletal, cardiac and smooth muscles.

Vitamin E has consistenly been shown to play a role in immune function by stimulating immunoglobulin formation, in DNA repair, and other metabolic processes. Vitamin is also critical to maintaining liver and muscle health, and normal reproduction.

Vitamin E exists in eight different forms. Each form has its own biological activity, which is the measure of potency or functional use in the body. Alpha-tocopherol (α-tocopherol) is the name of the natural, most active form of Vtamin E.

Vitamin E in feed supplements is usually sold as alpha-tocopheryl acetate, a more stable but less bioavailable form. This synthetic form is labeled "D, L" while the natural form is labeled "D". The synthetic form is only half as active as the natural form in humans, according to the USDA, and largely unavailable to newborn calves.

Most Advanced

Natural Vitamin E

Available in Clear,

Sterile, Aqueous Liquid as

Emcelle Tocopherol

& Injectible as

Vital E-300

Emcelle

Shown in Research To:

Aid & Prevent Vitamin E Deficiencies

Increase Gain

Improve Feed Efficency

Reduce Medication Costs

Best performance

was shown when

Emcelle Tocopherol

was combined with

Injectable

Vital E-300

Emcelle Tocopherol Is More Bioavailable Than

Vitamin E Acetate

TWO Steps are required for absorption of Vitamin E Acetate (esters) which a NOT required for Emcelle Tocopherol:

1. The ester has to be removed by the action of esterase enzymes in the intestinal tract. If there is a deficiency of hte enzyme, absorption will be hindered.

2. The second step is micellization. After the ester has been removed, the free tocopherol must be micellized by the action of bile salts to convert oil-soluble tocopherol into a water-soluble form that can be absorbed.

EMCELLE®-TOCOPHEROL is a clear, micellized, water-dispersible, liquid solution of vitamin E. The product is specially formulated for use in liquid diets, mixed into drinking water, or top-dressed onto dry feeds at time of feeding.The micellization process enhances the ability of animals to utilize vitamin E. The process allows the fat-soluble vitamin E to be absorbed more readily than dry, oil-based, or emulsion-forms of vitamin E. The product has shown to be effective in all classes of animals tested.

Feeding Directions

Emcelle Tocopherol (Available exclusively to the veal industry from Nouriche Nutrition)

For First 20 Days - Feed 0.4 ml of Emcelle per calf daily for first 20 days to provide 200 I.U. Vitamin E as d-alpha-tocophrol;

One bottle of Emcelle will feed 125 calves.

Vital E-300 (Schering Plough Animal Health:

Upon Arrival - Inject 5 ml to provide 1500 I.U. d-alpha-tocopherol upon arival - 1 shot.

Why Calves Need Vitamin E

From Emcelle Tocopherol

Calves are born with very low levels of Vitamin E due primarily to poor placental transfer. Thus the neonatal calf is immediately dependant on colostrum and subsequently milk or milk replacer to provide adequate Vitamin E to meet its needs. Colostrum contains 8 times more Vitamin E activity than normal milk.

Vitamin E is not synthesized in the body and must be obtained from dietary sources. The published NRC requirement for Vitamin E for calves is 50 I.U. per kg dry matter (RNS, 2001).

However, not all Vitamin E supplementation are effectively utilized by the young nursing calf.